Check out Joe’s full review for each program, plus his conclusion on which is best here: Price: $30 Pros: Blacklist, whitelist, regular expression matching; image spam filtering; several other filtering options. Cons: No Bayesian filter; no IMAP support; no direct integration with email clients; cluttered interface; poor documentation. 2) JunkMatcher Price: Free (donations accepted) Pros: Bayesian filter; regular expressions; wide variety of actions available for suspected spam. Cons: Complex UI; no universal binary version; nearly two years since last update. 3) Personal Antispam X4 Price: $50 Pros: Bayesian filter; blacklist; whitelist; attachment checking; integrates well with Mail and Entourage. Cons: Adds lots of extra stuff (of questionable value) to your system; expensive. 4) Spamfire Price: $40 (includes one-year subscription to filter updates; renewal costs range from $10 for one year to $35 for a permanent subscription). Pros: Automated setup for most clients works well; good configuration options. Cons: Weak IMAP support; poor integration with email clients; ongoing subscription cost is a drag. 5) SpamSieve Price: $30 Pros: Bayesian filter with adjustable sensitivity; blacklist; whitelist; regular expressions; excellent integration with email clients; nearly invisible operation. Cons: Limited actions available for suspected spam; some initial manual training required. 6) SpamSweep Price: $25 Pros: Bayesian filter; whitelist; domain and relay blacklists. Cons: No IMAP support; limited configuration options; awkward procedure for handling false positives; sketchy documentation. Spam Filters for Your Mac: Six Choices – [EarthWeb]